反应 #1466010

反应方程式

4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide

N-acetyl-L-cysteine

→

title compound

收率 81.6%

2-Acetylamino-3-[2-(4-sulfamoylphenylcarbamoyl)phenyldisulfanyl]-propionic acid

收率 81.6%

反应条件

后处理

1. 1
   其他This compound was prepared
2. 2
   洗涤The product was washed with ether
3. 3
   其他dried in vacuo

实验过程

This compound was prepared according to the method of Example 132 using 0.8 g (2.4 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.39 g (2.4 mmol) of N-acetyl-L-cysteine. The product was washed with ether and dried in vacuo to give 0.92 g of the title compound, mp 218°-220° C.

来源