反应 #1463483

反应方程式

cyclohexane

4-(4-propylphenyl)phenylcyclohexane

toluene

formic acid

→

3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal

反应条件

后处理

1. 1
   温度heating the mixture
2. 2
   温度under reflux for 5 hours
3. 3
   洗涤washing the reaction mixture with water after completion of the stirring
4. 4
   干燥drying over anhydrous magnesium sulfate
5. 5
   浓缩concentrating under reduced pressure
6. 6
   其他isolating the resulting yellow oil

实验过程

This cyclohexane derivative (11.8 g, 30 mmols) was dissolved in toluene (100 ml), followed by adding formic acid (5 ml), heating the mixture under reflux for 5 hours, washing the reaction mixture with water after completion of the stirring, drying over anhydrous magnesium sulfate, concentrating under reduced pressure and isolating the resulting yellow oil to obtain 3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal. This product is used in the subsequent reaction with any purification.

来源