反应 #1375828

ord-b12c9a219af34464acfe90a7804b2d37

反应方程式

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
tocol
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol
O=CO
formic acid
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol
→
C/C(=C\CO)CCC[C@H](C)CCC[C@H](C)CCCC(C)C
phytol
Oc1ccc(O)cc1
hydroquinone

反应物

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
tocol
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol
O=CO
formic acid
—
( X )
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)ccc2O1
Tocol

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Tocol (2-methyl-2-(4,8,12-trimethyltridecyl)-6-chromanol) and its derivatives are noted for antioxidant activity. Merck 9th Ed. at page 1221, which is hereby incorporated by reference. Tocol is a colorless viscous oil having a molecular weight of about 388.61 and a boiling point of about 165° C. to about 175° C. at 0.001 atm. Merck 9th Ed. at page 1221. The structural formula of tocol is given in formula (X) below: ##STR7## Tocol can be produced by condensation of hydroquinone and phytol in the presence of anhydrous formic acid. Merck 9th Ed. at page 1221.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US05747162uspto-grants-1998_05