反应 #1365717

反应方程式

Z-Leu-OH

N-hydroxysuccinimide

DCC

→

Z-Leu-OSu

溶剂

dioxane

反应条件

后处理

1. 1
   其他room temp overnight
2. 2
   过滤After filtering off the by product urea
3. 3
   浓缩the filtrate was concentrated

实验过程

Z-Leu-OH (15.92 g) and N-hydroxysuccinimide (6.9 g) were dissolved in dioxane and cooled to 0° C. To the cooled solution, DCC was added and stirred at 0° C. for 0.5 h, then room temp overnight. After filtering off the by product urea, the filtrate was concentrated to give crude Z-Leu-OSu as an oil.

来源