反应 #1350566

反应方程式

( 1 )

Cyanuric chloride

Potassium hydrogen carbonate

propylamine

Cyanuric chloride

→

4,6-dichloro-2-propylamino-1,3,5-triazine

溶剂

water

acetone

反应条件

后处理

1. 1
   温度cooled in an ice/acetone bath
2. 2
   温度while maintaining the temperature below 0° C
3. 3
   workup.STIRRINGstirred for 1 hour at room temperature
4. 4
   其他The acetone was evaporated off under reduced pressure
5. 5
   workup.ADDITIONthe residue (300 ml) was poured into water (11)
6. 6
   过滤The resulting white solid was filtered
7. 7
   洗涤washed with water
8. 8
   其他dried under vacuum

实验过程

Cyanuric chloride (1) (36.9 g, 0.2 mole) was dissolved in acetone (600 ml) and cooled in an ice/acetone bath. Potassium hydrogen carbonate (25.03 g,0.25 mole) was dissolved in water (150 ml) with propylamine (11.82 g, 0.2 mole) and added dropwise to the solution of (1) while maintaining the temperature below 0° C. The mixture was stirred for 1 hour at 0° C. and then stirred for 1 hour at room temperature. The acetone was evaporated off under reduced pressure and the residue (300 ml) was poured into water (11). The resulting white solid was filtered, washed with water and dried under vacuum.

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