反应 #1340579

反应方程式

octadecyl succinic anhydride

6-amino-1-hexanol

→

N-(6-hydroxyhexyl)octadecyl succinimide

收率 69.0%

反应条件

后处理

1. 1
   其他A 300 mL reaction flask
2. 2
   其他the resulting mixture was reacted at 160° C. for 3.5 hours under continuous nitrogen purging and with vigorous stirring
3. 3
   其他The reaction product was purified by silica gel column chromatography

实验过程

A 300 mL reaction flask was charged with 63.2 g of octadecyl succinic anhydride (manufactured by Tokyo Chemical Industry Co., Ltd.) and 21.0 g of 6-amino-1-hexanol (manufactured by Tokyo Chemical Industry Co., Ltd.), and the resulting mixture was reacted at 160° C. for 3.5 hours under continuous nitrogen purging and with vigorous stirring. The reaction product was purified by silica gel column chromatography, yielding 55.87 g of N-(6-hydroxyhexyl)octadecyl succinimide (yield: 69.0%).

来源