反应 #1276

反应方程式

Cis-1,2-indandiol

acetonitrile

sulfuric acid

Water

→

cis-1-amino-2-indanol

反应条件

后处理

1. 1
   温度with gradual warming to 0° C
2. 2
   温度the mixture heated to 80° C. for 1 hour

实验过程

Cis-1,2-indandiol (1.0 g) was dissolved in acetonitrile (20 mL), cooled to -40° C., and fuming sulfuric acid (21% SO3, 0.8 mL) was added. The mixture was aged for 1 hour with gradual warming to 0° C. Water was added and the mixture heated to 80° C. for 1 hour to provide an aqueous solution of cis-1-amino-2-indanol.

来源