反应 #1269870

反应方程式

tert-butyl 7-benzoyl-2,7-diazaspiro[4.4]nonane-2-carboxylate

→

phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone

溶剂

TFA

CH2Cl2

反应条件

后处理

1. 1
   其他After removal of solvents
2. 2
   其他the residue, phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone, was used in the further reactions without purification

实验过程

tert-butyl 7-benzoyl-2,7-diazaspiro[4.4]nonane-2-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, phenyl(2,7-diazaspiro[4.4]nonan-2-yl)methanone, was used in the further reactions without purification.

来源