反应 #1269868

反应方程式

tert-butyl 7-(1-phenyl-1H-tetrazol-5-yl)-2,7-diazaspiro[4.4]nonane-2-carboxylate

→

2-(1-phenyl-1H-tetrazol-5-yl)-2,7-diazaspiro[4.4]nonane

溶剂

TFA

CH2Cl2

反应条件

后处理

1. 1
   其他After removal of solvents
2. 2
   其他the residue, crude 2-(1-phenyl-1H-tetrazol-5-yl)-2,7-diazaspiro[4.4]nonane, was used in the further reactions without purification

实验过程

tert-butyl 7-(1-phenyl-1H-tetrazol-5-yl)-2,7-diazaspiro[4.4]nonane-2-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, crude 2-(1-phenyl-1H-tetrazol-5-yl)-2,7-diazaspiro[4.4]nonane, was used in the further reactions without purification.

来源