反应 #1269808
ord-2ef4bb7b47c9439393575797c4fb9ffa
反应方程式
7-epi-taxol
paclitaxel
→
Baccatin III
试剂
无
反应条件
详细条件
See reaction.notes.procedure_details.
后处理
- 1其他Degradation products were formed in the same proportions as in the experiments
- 2其他conducted under room temperature but in significantly lower quantities
- 3其他Its amounts formed during 32 h
- 4温度increased from about 3% at pH 7.0 to about 10% at pH 8.0 (see Table 11)
实验过程
Degradation products were formed in the same proportions as in the experiments conducted under room temperature but in significantly lower quantities. Again, 7-epi-taxol was the main degradation product of paclitaxel. Its amounts formed during 32 h increased from about 3% at pH 7.0 to about 10% at pH 8.0 (see Table 11). Baccatin III and 10-deacethyltaxol were formed for about 5 to 6% at pH 8.0.