反应 #1265375

反应方程式

4-vinylbenzylchloride

morpholine

→

product

收率 86.4%

N-(4-Vinylphenyl)methylmorpholine

收率 86.4%

溶剂

methanol

反应条件

后处理

1. 1
   浓缩The mixture was then concentrated in vacuo
2. 2
   其他the resulting residue was partitioned between 1M hydrochloric acid and water [sic]
3. 3
   洗涤The acidic phase was washed with ether
4. 4
   萃取This aqueous phase was extracted with ether
5. 5
   其他This organic phase was dried
6. 6
   浓缩concentrated in vacuo

实验过程

20 ml (0.14 mol) of 4-vinylbenzylchloride and 25 ml (0.28 mol) of morpholine were refluxed in 150 ml of methanol for 3 h. The mixture was then concentrated in vacuo, and the resulting residue was partitioned between 1M hydrochloric acid and water [sic]. The acidic phase was washed with ether and then made alkaline with 2M sodium hydroxide solution. This aqueous phase was extracted with ether. This organic phase was dried and concentrated in vacuo, resulting in 24.6 g of the product.

来源