反应 #1256764

反应方程式

ammonium acetate

ethyl cyanoacetate

1-acetyl-cyclopropanecarboxylic acid ethyl ester

3-nitrobenzaldehyde

→

product

收率 10.0%

1-[5-Cyano-4-(3-nitro-phenyl)-6-oxo-1,6-dihydro-pyridin-2-yl]-cyclopropanecarboxylic acid ethyl ester

收率 10.0%

反应条件

实验过程

In analogy to GP 1, reaction of 30.8 g ammonium acetate (400 mmol), 11.3 g ethyl cyanoacetate (100 mmol), 15.6 g 1-acetyl-cyclopropanecarboxylic acid ethyl ester (100 mmol), and 15.1 g 3-nitrobenzaldehyde (100 mmol) yielded 3.5 g product (10% yield).

来源