反应 #1253203

反应方程式

chlorine

3,4-dimethyl-2-pyrazolin-5-one

→

3,4-dimethyl-4-chloro-2-pyrazolin-5-one

溶剂

1,2-dichloroethane

反应条件

后处理

1. 1
   其他After the reaction
2. 2
   温度the reaction mixture was cooled
3. 3
   过滤filtered
4. 4
   workup.DISTILLATIONThe solvent was then distilled off
5. 5
   其他The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether

实验过程

A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.

来源