反应 #1248813

ord-7efaf3d8aede43c6ad7f9fb6317b3920

反应方程式

OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
O=C(CO)[C@@H](O)[C@H](O)CO
xylulose
→
O=C[C@H](O)[C@@H](O)[C@H](O)CO
xylose
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol

反应物

OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
O=C(CO)[C@@H](O)[C@H](O)CO
xylulose

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他produced in Candida sp strains

实验过程

Paying attention to the fact that xylitol produced in Candida sp strains is reduced by its conversion to xylulose by xylitol dehydrogenase, the present inventors have developed xylitol dehydrogenase-inactivated Candida tropicalis mutant, in which xylitol produced from xylose can no longer be used for cell growth, and thus xylose can be bioconverted to xylitol with a theoretical yield of 100% (Ko, B. S. et. al., Appl. Environ. Microbiol. 72:4207-4213, 2006). Thus, the present inventors filed an application for the protection of an invention relating to a method of producing xylitol in high yield using a xylitol-producing strain, in which the expression of xylitol dehydrogenase is inhibited (Korean Patent Application No. 10-2005-0079751, filed on Aug. 30, 2005).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07820414B2uspto-grants-2010_10