反应 #1244318

反应方程式

[bis(trifluoroacetoxy)iodo]benzene

octyl 8-hydroxyquinoline-2-carboxylate

→

octyl 5,8-dioxo-5,8-dihydroquinoline-2-carboxylate

收率 91.2%

溶剂

MeCN water

CH2Cl2

CH2Cl2

反应条件

后处理

1. 1
   洗涤washed with water
2. 2
   其他dried in vacuo

实验过程

To a stirred solution of [bis(trifluoroacetoxy)iodo]benzene (PIFA) (258 mg, 0.6 mmol) in MeCN/water 2:1 (3 ml) at 0° C. was added octyl 8-hydroxyquinoline-2-carboxylate (71 mg, 0.24 mmol) in CH2Cl2 (1 ml). The solution was stirred for 20 min, poured into CH2Cl2 (20 mL), washed with water and dried in vacuo to give octyl 5,8-dioxo-5,8-dihydroquinoline-2-carboxylate (69 mg, 90%).

来源