反应 #1244259

反应方程式

methyl ethyl ketone

quinizarin

potassium carbonate

ethyl sulfate

→

1,4-Diethoxyanthraquinone

反应条件

后处理

1. 1
   过滤The reaction was filtered hot through Celite
2. 2
   其他The solution was evaporated on a rotary evaporator until crystallization
3. 3
   温度After cooling in an ice bath
4. 4
   过滤the crystals were filtered
5. 5
   洗涤rinsed with Et2O
6. 6
   其他sucked dry
7. 7
   其他dried overnight in a vacuum oven at 70° C

实验过程

A mixture of quinizarin (20.0 g, 83.5 mmol), potassium carbonate (76 g, 550 mmol) and ethyl sulfate (38.6 g, 250 mmol) was refluxed in methyl ethyl ketone (MEK, 950 mL) for 24 hrs. The reaction was filtered hot through Celite using additional hot MEK. The solution was evaporated on a rotary evaporator until crystallization began, then the reaction was allowed to sit overnight. After cooling in an ice bath, the crystals were filtered, rinsed with Et2O, sucked dry, then dried overnight in a vacuum oven at 70° C. The yield was 14.0 g (57%) of yellow/orange crystals.

来源