反应 #1244247

反应方程式

propanoyl chloride

4-Phenylazophenol

triethylamine

→

product

收率 72.0%

Propionic acid 4-phenylazo-phenyl ester

收率 72.0%

溶剂

ether

ether

反应条件

后处理

1. 1
   其他reaction
2. 2
   洗涤The reaction mixture was washed with water
3. 3
   workup.ADDITIONdilute acid and brine
4. 4
   干燥dried with magnesium sulfate
5. 5
   其他The solvent was evaporated

实验过程

4-Phenylazophenol (0.25 g, 1.26 mmoles) was dissolved in ether (5-10 mL) and triethylamine (0.26 mL) was added. Then propanoyl chloride (0.14 g 1.5 mmoles) in ether (1 mL) was added dropwise at room temperature. The mixture was stirred and reaction was rapidly completed. The reaction mixture was washed with water, dilute acid and brine and dried with magnesium sulfate. The solvent was evaporated to give 0.23 g (72%) of product. 1H NMR (CDCl3) δ=1.16 (3H, t, J=7.7), 2.40 (2H, q J=7.7), 7.25 (2H, m), 7.40-7.58 (3H, m), 7.88-8.0 (4H, m) ppm.

来源