反应 #1216

反应方程式

1-tridecen-3-ol

m-chloroperbenzoic acid

benzene

→

1,2-epoxy-3-tridecanol

收率 74.0%

溶剂

hexane

反应条件

后处理

1. 1
   其他A 500-ml flask equipped with a stirrer
2. 2
   其他Solids deposited were separated by filtration
3. 3
   workup.DISTILLATIONthe solvent was distilled off under reduced pressure
4. 4
   其他The resultant residue was purified by column chromatography on silica gel

实验过程

A 500-ml flask equipped with a stirrer was charged with 23.8 g (0.12 mol) of 1-tridecen-3-ol, 25.0 g (0.145 mol) of m-chloroperbenzoic acid and 250 ml of benzene, and the contents were stirred at room temperature for 48 hours. After completion of the reaction, 200 ml of hexane. Solids deposited were separated by filtration, and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography on silica gel, thereby obtaining 19.0 g (yield: 74%) of 1,2-epoxy-3-tridecanol.

来源