反应 #12079

反应方程式

sodium chlorodifluoroacetate

chlorotriethoxysilane

→

chlorodifluoroacetic acid, triethoxysilyl ester

溶剂

Et2O

Et2O

反应条件

后处理

1. 1
   温度to warm up to room temperature
2. 2
   其他NaCl is removed by filtration and solution
3. 3
   其他evaporated to dryness

实验过程

15.246 g (0.10 mol) sodium chlorodifluoroacetate, is dissolved to 100 mL Et2O and cooled to −70° C. 19.7 mL (0.10 mol, 19.872 g) chlorotriethoxysilane in Et2O (50 mL) was added dropwise to reaction solution. The solution was stirred for over night allowing it to warm up to room temperature. NaCl is removed by filtration and solution evaporated to dryness to result clear colourless liquid, chlorodifluoroacetic acid, triethoxysilyl ester.

来源