反应 #11965

反应方程式

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

收率 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

收率 189.4%

溶剂

methanol

反应条件

后处理

1. 1
   其他After the reaction
2. 2
   其他the solvent was removed by distillation
3. 3
   其他the residue was dried

实验过程

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

来源