反应 #1178484

反应方程式

4-Benzyl-2,6-dimethylmorpholine

acetic acid

→

title compound

收率 92.0%

2,6-Dimethylmorpholine acetate

收率 92.0%

溶剂

ethanol

反应条件

后处理

1. 1
   其他The catalyst was separated by filtration
2. 2
   浓缩the reaction liquor was concentrated under reduced pressure
3. 3
   其他dried

实验过程

4-Benzyl-2,6-dimethylmorpholine (10.72 mg, 45.76 mmol) was dissolved in acetic acid (10 mL) and ethanol (200 mL), and 10% palladium hydroxide/carbon (5 g) was added thereto. The mixture was stirred for two days at room temperature under a hydrogen stream at normal pressure. The catalyst was separated by filtration, and then the reaction liquor was concentrated under reduced pressure and dried, to obtain the title compound (7.36 g, 92%) as an oily matter. This compound was used in the subsequent reaction without performing further purification.

来源