反应 #1178452

反应方程式

tert-butyl (R)-2-(4-chlorophenylcarbamoyl)pyrrolidine-1-carboxylate

→

(R)-2-(4-chlorophenylcarbamoyl)pyrrolidinium chloride

溶剂

HCl

dioxane

反应条件

后处理

1. 1
   其他The reaction mixture is evaporated
2. 2
   其他dried

实验过程

4.00 g (12.3 mmol) of tert-butyl (R)-2-(4-chlorophenylcarbamoyl)pyrrolidine-1-carboxylate are dissolved in 20 ml of 4N HCl in dioxane and left at room temperature for 2 hours. The reaction mixture is evaporated and dried, giving (R)-2-(4-chlorophenylcarbamoyl)pyrrolidinium chloride as a slightly brownish solid; ESI 225.

来源