反应 #1178395

反应方程式

4,4′-dihydroxybenzophenone

→

1,1,2,2-tetrakis(4-hydroxyphenyl)ethylene

收率 83.0%

溶剂

THF

反应条件

后处理

1. 1
   温度was refluxed for 20 h
2. 2
   过滤filtered
3. 3
   其他The filtrates were evaporated
4. 4
   其他the crude product was purified by a silica gel column
5. 5
   其他DHTPE was obtained as slight yellow powder of 83% yield

实验过程

A suspension of 4,4′-dihydroxybenzophenone (3.0 g, 14.0 mmol), 1 equiv of TiCl4 (1.54 ml, 14.0 mmol), and 2 equiv of Zn dust (1.83 g, 28.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using ethyl acetate (EA) as eluent. DHTPE was obtained as slight yellow powder of 83% yield.

来源