反应 #1178394

反应方程式

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

收率 91.0%

溶剂

THF

反应条件

后处理

1. 1
   温度was refluxed for 20 h
2. 2
   过滤filtered
3. 3
   其他The filtrates were evaporated
4. 4
   其他the crude product was purified by a silica gel column

实验过程

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

来源