反应 #1178388

ord-9b6ecdf8dfcc434aa8562bd50920dea3

反应方程式

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
mannitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
收率 119.7%

反应物

试剂

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他the resulting wet granules were dried

实验过程

The procedure of Example 1 was repeated except that 300 mg of mannitol was dissolved in a mixture of 10 mg of water and 10 mg of ethanol, the solution was subjected to wet granulation, and the resulting wet granules were dried and used as the sugar alcohol, not 300 mg of xylitol, to obtain an inventive rapidly disintegrating formulation tablet.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US08127516B2uspto-grants-2012_03