反应 #11634

反应方程式

3-hydroxymethylene-6-(3-methoxy-phenyl)-1,3-dihydro-indol-2-one

4-morpholin-4-yl-phenylamine

→

compound

6-(3-Methoxy-phenyl)-3-{[4-morpholin-4-yl-phenylamino)-methylene]-1,3-dihydro-indol-2-one

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   其他The named compound is prepared
2. 2
   其他solvent evaporation in vacuo, trituration
3. 3
   过滤with isopropanol and filtration the reaction

实验过程

The named compound is prepared by refluxing 0.020 gms E & Z 3-hydroxymethylene-6-(3-methoxy-phenyl)-1,3-dihydro-indol-2-one with 0.020 gms. 4-morpholin-4-yl-phenylamine in tetrahydrofuran (0.33 mL) for 2 days. Following cooling to room temperature, solvent evaporation in vacuo, trituration with isopropanol and filtration the reaction yields the named compound as a solid in the amount of 15.7 mg.

来源