反应 #1135838

反应方程式

1-fluoro-2-nitrobenzene

cyclopropyl amine

→

N-cyclopropyl-2-nitroaniline

收率 96.2%

溶剂

ethanol

反应条件

后处理

1. 1
   浓缩concentrated
2. 2
   其他The residue was purified by biotage column chromatography

实验过程

To a solution of 1-fluoro-2-nitrobenzene (0.50 g, 3.5 mmol) in ethanol was added cyclopropyl amine (0.60 g, 10.5 mmol). The solution was heated to 80° C. overnight and concentrated. The residue was purified by biotage column chromatography to give N-cyclopropyl-2-nitroaniline (0.60 g)

来源