反应 #1118770

反应方程式

5-Hexenoic acid

toluene sulfonic acid monohydrate

→

title compound

收率 84.0%

Methyl 5-Hexenoate

收率 84.0%

溶剂

methanol

反应条件

后处理

1. 1
   温度The solution was cooled
2. 2
   浓缩concentrated
3. 3
   workup.ADDITIONthen poured into ether/water
4. 4
   干燥The ether layer was dried over sodium sulfate
5. 5
   浓缩concentrated

实验过程

5-Hexenoic acid (4.9 g, 42.9 mmol) was refluxed in 80 ml of methanol with catalytic p toluene sulfonic acid monohydrate for 40 hours. The solution was cooled and concentrated then poured into ether/water. The ether layer was dried over sodium sulfate and concentrated to give 4.6 g (35.9 mmol), 84% of the title compound.

来源