反应 #1036
ord-785f3c16cc454b2f8882766f14740ddd
反应方程式
1-chloro-1,2-dibromotrifluoroethane
1,1,2-trichlorotrifiuoroethane
vinylidene chloride
persulfate sodium formate
→
4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid
3,4- dichloro-3,4,4-trifluorobutanoic acid
反应物
试剂
无
溶剂
反应条件
详细条件
See reaction.notes.procedure_details.
实验过程
A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) or 1,1,2-trichlorotrifiuoroethane (X) with vinylidene chloride in the presence of ammoninm persulfate/sodium formate/air in DMF to give 4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid (VIII) or 3,4- dichloro-3,4,4-trifluorobutanoic acid (XI).