反应 #1005971

反应方程式

2′-ethylsulfonylacetophenone

phenyltrimethylammonium tribromide

sodium thiosulfate

→

2-bromo-2′-ethylsulfonylacetophenone

收率 164.0%

溶剂

THF

反应条件

后处理

1. 1
   萃取the mixture was extracted with t-butyl methyl ether
2. 2
   洗涤The organic layer was washed with water
3. 3
   干燥dried over anhydrous magnesium sulfate
4. 4
   浓缩concentrated under reduced pressure

实验过程

A mixture of 1.0 g of 2′-ethylsulfonylacetophenone, 1.86 g of phenyltrimethylammonium tribromide and 10 ml of THF was stirred at room temperature for 3 hours. A 10% aqueous sodium thiosulfate solution was poured to the reaction mixture, and the mixture was extracted with t-butyl methyl ether. The organic layer was washed with water and dried over anhydrous magnesium sulfate, then concentrated under reduced pressure to obtain 1.37 g of 2-bromo-2′-ethylsulfonylacetophenone.

来源