Реакция #9967

Уравнение реакции

thionyl chloride

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoic acid

→

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoyl chloride

Растворители

ethyl acetate

Условия реакции

Обработка

1. 1
   Температураcooled
2. 2
   Концентрированиеconcentrated under reduced pressure, co-evaporated with ethyl acetate (2×100 mL)
3. 3
   Другоеthe oil so obtained

Методика

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoic acid (1.1 g, 26.92 mMole) was suspended in ethyl acetate (100 mL) to which was added several drops of dimethylformamide and thionyl chloride (10.0 mL, 134.6 mMole). The mixture was heated at 70° C. for 1.5 hours, cooled, concentrated under reduced pressure, co-evaporated with ethyl acetate (2×100 mL) and the oil so obtained used as such in the next step of the reaction sequence.

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