Реакция #992693

ord-2ba0fedd47514f2ea231865f164fe779

Уравнение реакции

O=C(O)CC(O)C(=O)O
DL-Malic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
O=C=O
carbon dioxide
→
NNC(N)=[NH2+].NNC(N)=[NH2+].O=C([O-])CC(O)C(=O)[O-]
Bis(aminoguanidinium) DL-Malate

Реактанты

O=C(O)CC(O)C(=O)O
DL-Malic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
O=C=O
carbon dioxide

Реагенты

Нет

Растворители

O
water

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеThe water was removed in vacuo
  2. 2
    Температураwith heating to approximately 90° C. for 4 hours
  3. 3
    ДругоеThe product was isolated as a white solid

Методика

DL-Malic acid (2.0 g, 14.92 mmol) was dissolved in 5 ml of distilled water. Aminoguanidine bicarbonate (4.06 g, 29.83 mmol) was added in portions at room temperature (carbon dioxide gas was evolved) and the reaction was stirred at room temperature for 18 hours. The water was removed in vacuo with heating to approximately 90° C. for 4 hours. The product was isolated as a white solid.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US08012277B2uspto-grants-2011_09