Реакция #9903

Уравнение реакции

6-cyclopentylidene-hexan-1-ol

→

6-cyclopentyl-hexan-1-ol

Выход 111.4%

Растворители

MeOH

Условия реакции

Обработка

1. 1
   ДругоеThe catalyst was removed by filtration
2. 2
   Другоеthe filtrate was evaporated under reduced pressure

Методика

A solution of 6-cyclopentylidene-hexan-1-ol (1.15 g, 6.85 mmol) in MeOH (50 mL) was hydrogenated with Pd—C (0.25 g, 10% w/w) in a Parr apparatus at 50 psi of H2 overnight. The catalyst was removed by filtration, and the filtrate was evaporated under reduced pressure to give 6-cyclopentyl-hexan-1-ol (1.30 g, 100%) as a colorless oil: 1H NMR (300 MHz, CDCl3) δ 3.63 (2H, t, J=6.6 Hz), 1.42–1.64 (6H, m), 1.20–1.40 (8H, m), 1.04(2H, m); 13C NMR (75 MHz, CDCl3) δ 63.28, 40.41, 36.43, 33.06, 33.00, 29.98, 29.04, 26.05, 25.47.

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