Реакция #985262

Уравнение реакции

2-(4-nitrophenyl)benzothiazole

tin (II) chloride dihydrate

→

2-(4-Aminophenyl)benzothiazole

Растворители

ethanol

Условия реакции

Обработка

1. 1
   Температураwas refluxed under N2 for 4 hrs
2. 2
   ДругоеAfter removing ethanol
3. 3
   Другоеby vacuum evaporation
4. 4
   workup.DISSOLUTIONThe residue was dissolved into ethyl acetate (20 ml)
5. 5
   Промывкаwashed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml)
6. 6
   Другоеdried
7. 7
   Другоеevaporated to dryness to givelo2 mg (97%) of the product

Методика

A mixture of 2-(4-nitrophenyl)benzothiazole (105 mg, 0.40 mmol) and tin (II) chloride dihydrate (205 mg, 0.91 mmol) in ethanol (20 mL) was refluxed under N2 for 4 hrs. After removing ethanol by vacuum evaporation. The residue was dissolved into ethyl acetate (20 ml), and washed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml), dried and evaporated to dryness to givelo2 mg (97%) of the product

Источник