Реакция #9848

Уравнение реакции

acetic acid

2-nitrotoluene

hexahydro-1,3,5-trihydroxy-1,3,5-triazine-2,4,6-trione

→

2-nitrobenzoic acid

2-nitrotoluene

Растворители

water

Условия реакции

Обработка

1. 1
   workup.ADDITIONThe autoclave was charged with 1 MPa of air
2. 2
   Другоеplaced in a heated oil bath
3. 3
   ДругоеAfter the completion of reaction
4. 4
   Температураto cool down the reaction mixture quickly

Методика

In an autoclave, 0.274 g of 2-nitrotoluene, 0.018 g of hexahydro-1,3,5-trihydroxy-1,3,5-triazine-2,4,6-trione (5% by mole relative to 2-nitrotoluene), 5 g of acetic acid, 0.003 g of cobalt (II) acetate.4H2O, 0.001 g of manganese(II) acetate.4H2O and 0.018 g of NO2 were placed. The autoclave was charged with 1 MPa of air and placed in a heated oil bath. The mixture was stirred at 150° C. for 14 hours. After the completion of reaction, the autoclave was placed on cold water to cool down the reaction mixture quickly. The resulting mixture was analyzed by gas chromatography and was found to yield 2-nitrobenzoic acid in 62% yield at 67% conversion of 2-nitrotoluene.

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