Реакция #9815

Уравнение реакции

6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

hydrogen

→

title compound

Выход 46.4%

6-Amino-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

Выход 46.4%

Растворители

THF

MeOH

Условия реакции

Обработка

1. 1
   ФильтрацияThe catalyst was filtered off
2. 2
   Другоеthe filtrate evaporated
3. 3
   Другоеthe residue chromatographed on silica

Методика

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

Источник