Реакция #981374

Уравнение реакции

6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid

thionyl chloride

→

title product

2-Chlorocarbonyl-6,11-dihydro-11-oxodibenz[b,e]oxepin

Условия реакции

Обработка

1. 1
   ТемператураHeat a solution of 5 gm
2. 2
   ДругоеEvaporate the reaction mixture under vacuum to dryness
3. 3
   ДругоеRepeat the evaporation with two 30 ml
4. 4
   ДругоеCrystallize the residue from diisopropyl ether

Методика

Heat a solution of 5 gm. of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid and 40 ml. of thionyl chloride under reflux for 20 minutes. Evaporate the reaction mixture under vacuum to dryness. Repeat the evaporation with two 30 ml. portions of carbon tetrachloride. Crystallize the residue from diisopropyl ether to obtain the title product.

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