Реакция #9746

ord-23f9c05e875c4e10a0232c503746efde

Уравнение реакции

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
Cc1ccc(C=O)cc1
4-methylbenzaldehyde
→
Cc1ccc(CCc2oc(-c3ccc(C(F)(F)F)cc3)cc2CO)cc1
{2-[2-(4-methylphenyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

Реактанты

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
Cc1ccc(C=O)cc1
4-methylbenzaldehyde

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

prepare from intermediate 62 and 4-methylbenzaldehyde

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07091237B2uspto-grants-2006_08