Реакция #96053

ord-3e3fc435b5a748fdb25a38e297db18be

Уравнение реакции

Br.Cc1ccc(N=C2SCC(O)(c3ccc(Cl)c(S(N)(=O)=O)c3)N2C)cc1
4-(4-chloro-3-sulfamoylphenyl)-3-methyl-2-(4-methylphenyl-imino)-thiazolidin-4-ol hydrobromide
CC(C)OC(C)C
diisopropyl ether
→
Br.Cc1ccc(N=c2scc(-c3ccc(Cl)c(S(N)(=O)=O)c3)n2C)cc1
4-(4-Chloro-3-sulfamoylphenyl)-3-methyl-2-(4-methylphenyl-imino)-4-thiazoline hydrobromide

Реактанты

Br.Cc1ccc(N=C2SCC(O)(c3ccc(Cl)c(S(N)(=O)=O)c3)N2C)cc1
4-(4-chloro-3-sulfamoylphenyl)-3-methyl-2-(4-methylphenyl-imino)-thiazolidin-4-ol hydrobromide
CC(C)OC(C)C
diisopropyl ether

Реагенты

Нет

Растворители

CCO
ethanol

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Температураunder reflux
  2. 2
    Фильтрацияthe crystals are filtered off

Методика

0.02 mole (9.8 g) of 4-(4-chloro-3-sulfamoylphenyl)-3-methyl-2-(4-methylphenyl-imino)-thiazolidin-4-ol hydrobromide are boiled in 120 ml of ethanol for 2 hours under reflux. After cooling to room temperature, 200 ml of diisopropyl ether are added and the crystals are filtered off. Melting point 265° C. (with decomposition).

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04346088uspto-grants-1982_08