Реакция #955948

Уравнение реакции

9-methylphenanthrene

NBS

→

product

Выход 89.7%

9-(bromomethyl)phenanthrene

Выход 89.7%

Растворители

benzene

Условия реакции

Обработка

1. 1
   Температураwas refluxed for 5 h
2. 2
   Другоеthe succinimide precipitated
3. 3
   Другоеwas removed by filtration
4. 4
   ПромывкаThe filtrate was washed by 15% NaOH
5. 5
   Сушкаdried over MgSO4
6. 6
   Концентрированиеconcentrated

Методика

A mixture of 9-methylphenanthrene (14.2 g, 74 mmol), benzoyl peroxide (40 mg, 0.16 mmol) and NBS (13.3 g, 74.6 mmol) in 210 mL of benzene was refluxed for 5 h. The reaction mixture was cooled to 0° C. and the succinimide precipitated was removed by filtration. The filtrate was washed by 15% NaOH, dried over MgSO4 and concentrated to yield 18 g of product which was used for the next step without further purification.

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