Реакция #955905

Уравнение реакции

3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene

acryl chloride

→

3-(1′-acryloyloxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene

Выход 92.2%

Растворители

pyridine

Условия реакции

Обработка

1. 1
   Другоеcontrolled at 0° C.
2. 2
   workup.DISSOLUTIONdissolved
3. 3
   Другоеthe reaction
4. 4
   Другоеresulting solution
5. 5
   Другоеwas purified via silica gel chromatography (mix solvent of hexane and ethyl acetate)

Методика

Subsequently, into pyridine controlled at 0° C., dissolved was 4.0 g of 3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene and added 0.50 g of acryl chloride for 30 minutes, followed by stirring 1 hour at room temperature. After finishing the reaction, resulting solution was purified via silica gel chromatography (mix solvent of hexane and ethyl acetate) to obtain 3.9 g of 3-(1′-acryloyloxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene (yield: 92%).

Источник