Реакция #955904

Уравнение реакции

nitric acid

1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene

→

3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene

Выход 76.2%

Растворители

dichloromethane

dichloromethane

Условия реакции

Обработка

1. 1
   workup.ADDITIONDispersed
2. 2
   workup.ADDITIONwas added
3. 3
   workup.ADDITIONInto the resulting dispersion, added
4. 4
   Фильтрацияsilica gel was filtered off
5. 5
   КонцентрированиеAfter the filtrate was concentrated under reduced pressure, 300 ml of methanol
6. 6
   workup.ADDITIONwas added
7. 7
   workup.STIRRINGstirred
8. 8
   ДругоеResulting precipitant
9. 9
   Фильтрацияwas filtered off

Методика

Dispersed was 63 g of silica gel into 21 g of nitric acid and 150 ml of dichloromethane was added. Into the resulting dispersion, added was a solution dissolving 5.0 g of 1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene in 30 ml of dichloromethane. After stirring for 15 minutes, silica gel was filtered off. After the filtrate was concentrated under reduced pressure, 300 ml of methanol was added and stirred. Resulting precipitant was filtered off to obtain 4.0 g of 3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene (yield: 76%).

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