Реакция #952652

Уравнение реакции

methyl 3-(R)-hydroxybutanoate

methyl iodide

→

methyl 3-(R)-hydroxy-2-(S)-methylbutanoate

Условия реакции

Обработка

1. 1
   ДругоеThis compound was prepared

Методика

This compound was prepared according to the procedure of Example 127, but the methyl 3-(R)-hydroxybutanoate was first alkylated with methyl iodide as described by Keck et al., (J. Org. Chem., 1985, 4317) to give methyl 3-(R)-hydroxy-2-(S)-methylbutanoate. The latter was transformed into the thiol according to the procedure of Example 127.

Источник