Реакция #95250

Уравнение реакции

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ДругоеThe solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   ПромывкаThe organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   Сушкаdried (MgSO4)
5. 5
   Другоеevaporated
6. 6
   Другоеto give 1.371 g

Методика

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

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