Реакция #94896

Уравнение реакции

decylamine

3-phenyl-3-(4-nitrophenyl)propenoyl chloride

→

N-Decyl-3-phenyl-3-(4-nitrophenyl)propenamide

Растворители

tetrahydrofuran

tetrahydrofuran

Условия реакции

Обработка

1. 1
   ДругоеThe solvent was removed by evaporation in vacuo
2. 2
   Другоеthe residue was partitioned between ethyl acetate and water
3. 3
   ДругоеThe layers were separated
4. 4
   Промывкаthe ethyl acetate layer was washed with water
5. 5
   Другоеdried
6. 6
   Другоеevaporated in vacuo

Методика

To a stirred solution of 5.89 g. of decylamine in 25 ml. of tetrahydrofuran was added a solution of 4.89 g. of 3-phenyl-3-(4-nitrophenyl)propenoyl chloride in 25 ml. of tetrahydrofuran, dropwise, during 20 minutes, at ice-bath temperature. The solvent was removed by evaporation in vacuo and the residue was partitioned between ethyl acetate and water. The layers were separated, and the ethyl acetate layer was washed with water, dried using sodium sulfate, and then evaporated in vacuo. This afforded 5.6 g. of the title compound, m.p. 91°-93° C.

Источник