Реакция #94891

ord-50fe5b40ef434616b743efc448ba991b

Уравнение реакции

CCCC(=O)c1ccc(OCCN(CC)CC)cc1Cl
2-diethylaminoethyl chloride hydrochloride
CCCC(=O)c1ccc(OCCN(CC)CC)cc1Cl
1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone
Cl.ClCCN1CCOCC1
N-(2-chloroethyl)morpholine hydrochloride
CCCC(=O)c1ccc(OCCN2CCOCC2)cc1Cl
1-[2-Chloro-4-(2-morpholinoethoxy)phenyl]-1-butanone

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеThis compound is prepared by essentially the same procedure
  2. 2
    ДругоеThe product is obtained as a colorless oil upon distillation in vacuo (0.3 mm.)

Методика

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1, Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)morpholine hydrochloride. The product is obtained as a colorless oil upon distillation in vacuo (0.3 mm.).

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04342782uspto-grants-1982_08