Реакция #9455

Уравнение реакции

Triethyl orthoformate

Meldrum's acid

biphenyl-3-ylamine

→

5-(biphenyl-3-ylaminomethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

Выход 95.5%

Условия реакции

Обработка

1. 1
   workup.ADDITIONtreated

Методика

Triethyl orthoformate (148 g, 1.00 mol), Meldrum's acid (137 g, 0.95 mol), and biphenyl-3-ylamine (155 g, 0.916 mol) were combined and treated according to the general procedure described in Part A of Example 1 to obtain 283 g of 5-(biphenyl-3-ylaminomethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione as a yellow solid.

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