Реакция #92935

Уравнение реакции

1-(4-methylphenyl)-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

Выход 11.0%

Растворители

diethyl ether

Условия реакции

Обработка

1. 1
   ДругоеThe reaction solvent was decanted
2. 2
   Промывкаthe residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with diethyl ether
5. 5
   Фильтрацияthe precipitated solid was collected by filtration
6. 6
   ДругоеThe solid was recrystallized from acetonitrile/diethyl ether

Методика

A solution 2.24 g (0.01 mol) of 1-(4-methylphenyl)-1-oxo-2-bromopropane and 0.9 g (0.011 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in acetonitrile. The resulting solution was diluted with diethyl ether and the precipitated solid was collected by filtration. The solid was recrystallized from acetonitrile/diethyl ether to afford 0.33 g of 1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as a solid. (11% yield) mp=175°-177° C.

Источник