Реакция #92934

Уравнение реакции

1-phenyl-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide

Выход 55.0%

Растворители

diethyl ether

Условия реакции

Обработка

1. 1
   ФильтрацияThe precipitated solid was collected by filtration
2. 2
   Промывкаwashed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in methanol
4. 4
   workup.ADDITIONThis solution was diluted with diethyl ether
5. 5
   Фильтрацияthe resulting white solid was collected by filtration
6. 6
   ДругоеThis solid was recrystallized from methanol/diethyl ether

Методика

A solution of 8 ml (0.047 mol) of 90% pure 1-phenyl-1-oxo-2-bromopropane and 4.25 g (0.052 mol) of 1-methylimidazole in 100 ml of diethyl ether was stirred at room temperature for approximately 24 hours. The precipitated solid was collected by filtration, washed with diethyl ether and dissolved in methanol. This solution was diluted with diethyl ether and the resulting white solid was collected by filtration. This solid was recrystallized from methanol/diethyl ether to afford 7.65 g of 1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide as white crystals. (55% yield) mp=167°-170° C.

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