Реакция #92933

Уравнение реакции

1-bromo-2-(2-methylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

Выход 34.0%

Растворители

diethyl ether

Условия реакции

Обработка

1. 1
   ДругоеThe reaction solvent was decanted
2. 2
   Промывкаthe residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONThe residue was dissolved in hot acetonitrile
4. 4
   Температураthe resulting solution was cooled
5. 5
   workup.ADDITIONdiluted with diethyl ether
6. 6
   ДругоеThe solid was collected
7. 7
   Другоеrecrystallized twice from acetonitrile/diethyl ether

Методика

A solution of 4.22 g (0.02 mol) of 1-bromo-2-(2-methylphenyl)-2-oxoethane, 2.64 g (0.032 mol) of 1-methylimidazole and 60 ml of diethyl ether was stirred at room temperature for approximately 17 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was dissolved in hot acetonitrile, and the resulting solution was cooled and diluted with diethyl ether. The solid was collected and recrystallized twice from acetonitrile/diethyl ether to afford 1.99 g of 1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as white needles. (34% yield) mp=152°-154° C.

Источник